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"Nuclear speckle fusion via long-range directional motion regulates speckle morphology after transcriptional inhibition"

Kim J, Han KY, Khanna N, Ha T & Belmont AS

J. Cell. Sci. doi: 10.1242/jcs.226563

"Facile single-molecule pull-down assay for analysis of endogenous proteins"

Croop B & Han KY

Phys. Biol. (invited article), https://doi.org/10.1088/1478-3975/ab0792

"Recent advancement of light-based single-molecule approaches for studying biomolecules"

Croop B*, Zhang C*, Lim Y*, Gelfand RM & Han KY

WIREs Syst. Biol. Med. (Review), 11, e1445

"Building a highly inclined swept tile microscope for extended field-of-view single-molecule imaging"

Tang J, Weng CH, Oleske JB & Han KY

JoVE, In press


"Extended field-of-view single-molecule imaging by highly inclined swept illumination"

Tang J & Han KY

Optica 5, 1063-1069 (2018) [bioRxiv 311753]

"Measuring molecular mass with light"

Han KY & Ha T

Nature Photonics 12, 380–381 (2018)

"Flat-field illumination for quantitative fluorescence imaging"

Khaw I*, Croop B*, Tang J, Möhl A, Fuchs U & Han KY

Opt. Express 26, 15276-15288 (2018)

"Single-molecule centroid localization algorithm improves the accuracy of fluorescence binding assays"

Hua B, Wang Y, Park S, Han KY, Singh D, Kim JH, Cheng W & Ha T

Biochemistry 57, 1572–1576 (2018)


"Endogenous alpha-synuclein protein analysis from human brain tissues using single-molecule pull-down assay"

Je G, Croop B, Basu S, Tang J, Han KY* & Kim YS*

Anal. Chem. 89, 13044-13048 (2017) [bioRxiv 188169]

"Spatially encoded fast single-molecule fluorescence spectroscopy with full field-of-view"
Tang J, Sun Y, Pang S & Han KY
Sci. Rep. 7, 10945 (2017)

"A genetically encoded fluorescent tRNA is active in live-cell protein synthesis"
Masuda I, Igarasgi T, Sakaguchi R, Nitharwal R, Takase R, Han KY, Leslie BJ, Liu C, Gamper H, Ha T, Sanyal S, Hou YM
Nucleic Acids Res. 45, 4081-4093 (2017)

Prior to CREOL

"A chemical controller of SNARE-driven membrane fusion that primes vesicles for Ca2+-triggered millisecond exocytosis"
Heo P, Yang Y, Han KY, Kong B, Shin J, Jung Y, Jeong C, Shin JH, Shin YK, Ha T, Kweon DH
J. Am. Chem. Soc. 138, 4512-4521 (2016)

"RESOLFT nanoscopy with photoswitchable organic fluorophores"
Kwon J, Hwang J, Park J, Han GR, Han KY*, Kim SK*
Sci. Reports 5, 17804 (2015)

"Tandem Spinach array for mRNA imaging in living bacterial cells"
Zhang J, Fei J, Leslie BJ, Han KY, Kuhlman TE, Ha T
Sci. Reports 5, 17295 (2015)

"Dual-color three-dimensional STED microscopy with a single high-repetition-rate laser"
Han KY, Ha T
Opt. Lett. 40, 2653-2656 (2015)

"An Improved surface passivation method for single-molecule studies"
Hua B, Han KY, ..., Ha T
Nature Methods 11, 1233-1236 (2014)

"Understanding the photophysics of the Spinach-DFHBI RNA aptamer-fluorogen complex to improve live cell RNA imaging"
Han KY, Leslie BJ, Fei J, Zhang J, Ha T
J. Am. Chem. Soc. 135, 19033-19038 (2013)

"Preparation of non-aggregated fluorescent nanodiamonds (FNDs) by non-covalent coating with a block copolymer and proteins for enhancement of intracellular uptake"
Lee JW, Lee S, Jang S, Han KY, Kim Y, Hyun J, Kim SK, Lee Y
Molecular BioSystems 9, 1004-1011 (2013)

"Dark state photophysics of nitrogen–vacancy centres in diamond"
Han KY*, Wildanger D*, Rittweger E, Meijer J, Pezzagna S, Hell SW, Eggeling C
New J. Phys. 14, 123002 (2012)

"Sharper low-power STED nanoscopy by time gating"
Vicidomini G*, Moneron G*, Han KY*, Westphal V, Ta T, Reuss M, Engelhardt J, Eggeling C, Hell SW
Nature Methods 8, 571-573 (2011)

"Metastable dark states enable ground state depletion microscopy of nitrogen vacancy centers in diamond with diffraction-unlimited resolution"
Han KY, Kim SK, Eggeling C, Hell SW
Nano Lett. 10, 3199-3203 (2010)

"Three-dimensional stimulated emission depletion microscopy of nitrogen-vacancy centers in diamond using continuous-wave light"
Han KY, Willig KI, Rittweger E, Jelezko F, Eggeling C, Hell SW
Nano Lett. 9, 3323-3329 (2009)

"STED microscopy reveals crystal colour centres with nanometric resolution"
Rittweger E*, Han KY*, Irvine SE*, Eggeling C, Hell SW
Nature Photonics 3,144-147 (2009)


"STED microscopy with pulsed excitation, continuous stimulation, and gated registration of spontaneously emitted fluorescence light"
Hell SW, Eggeling C, Engelhardt J, Han KY, Moneron G, Matthias R, Vicidomini G, Westphal V.
World patent WO 2012069076 A1; US patent US 20130256564 A1

Commercially available from Leica Microsystems (TCS SP8 STED 3x)

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